Currently, people have found that the cause of conduction disorders of the cardiac nervous system is a mutation in the SCN5A gene, located at chromosome 3p21.
Illustration photo: Sgtt.com.vn.
No warning signs
According to Dr. Vu Duc Thinh, Head of Intensive Care Department, Central E Hospital, in the 1980s, unexplained sudden death at night was a syndrome with high frequency in Southeast Asian countries.
Then, in the early 1990s, this disease was described in Thailand, the Philippines, Japan… Therefore, this disease is called Lai Tai in Thai or Bangunguttheo in the Philippine language, or Pokkuri in Japanese – both meanings.
The frequency of Brugada syndrome is currently unknown, but according to some reports, the incidence of this syndrome is about 5/10,000 people.
Many people with Brugada syndrome do not have symptoms so they are not diagnosed until they have arrhythmia or fainting during an electrocardiogram.
To date, determining whether a patient’s frequent episodes of fainting or palpitations are caused by this syndrome is usually not difficult.
Echocardiography may also be used to diagnose other heart conditions that can cause arrhythmias.
Difficult to treat, impossible to prevent
Although the pathogenesis is well understood, until now, treatment of Brugada syndrome remains very difficult.
Preventing Brugada syndrome is impossible because this is a genetic disease.